Advantages ‌

Excellent polymer dissolving capacity ‌
HFIP is one of the few solvents that can efficiently dissolve high-crystallinity, low-polarity polymers such as PLGA, PCL, and gelatin. Its strong hydrogen bond donor properties and high polarity enable it to achieve stable injection of high-concentration solutions in ‌ solvent casting 3D printing ‌, making it suitable for electrostatic direct writing (MEW) technology of micron-scale fiber structures.

Rapid evaporation promotes precise forming ‌
Its low boiling point (58-60 °C) and high vapor pressure characteristics enable the solvent to evaporate rapidly after extrusion, significantly shortening the curing time, reducing fiber collapse, and enhancing ‌ structural resolution and interlayer accuracy ‌. It is particularly suitable for high-precision bioprint scenarios such as tissue engineering scaffolds.

Build a high-performance conductive network ‌
In FDM composites, HFIP can pseudodope polyaniline (PANI), promoting the formation of a ‌ organic-inorganic hybrid conductive pathway ‌ with carbon nanofibers (CNF), effectively reducing the percolation threshold, enhancing the electromagnetic shielding performance (SET up to 58.7 dB), and alleviating the anisotropy problem caused by fiber orientation in traditional printing.

Surface activation potential ‌
In non-mainstream applications, its strong wettability and solubility suggest that it may be superior to isopropyl alcohol (IPA) in the pretreatment of ‌ printing substrates ‌, and has a stronger cleaning and activation ability for fluorine-containing or hydrophobic materials, potentially enhancing the adhesion of the first layer.

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