27776-21-2
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Product Overview |
2,2'-Azobis[2-(2-imidazolin-2-yl)propane] Dihydrochloride (VA-044, CAS No. 27776-21-2) is a water-soluble azo-type polymerization initiator widely applied for aqueous polymer synthesis. It is particularly suitable for low-temperature polymerization of water‑soluble vinyl monomers and emulsion polymerization systems.
Different from oil-soluble azo initiators, VA-044 contains no cyano groups in its molecular structure, bringing better environmental performance and lower toxicity of decomposition products.
VA-044 can also be used in the production of polyacrylamide, polyacrylic acid and styrene-acrylate copolymer latexes, where its chemical structure enables low‑temperature decomposition, high initiation efficiency and good water solubility. It helps maintain steady reaction rates and reduces the risk of runaway polymerization during production.
VA-044-initiated polymer systems are also adopted for selected water-borne polymer materials, flocculant intermediates and water-based adhesive applications. End products using VA-044 show consistent molecular weight distribution and reliable batch-to-batch stability.
Technical Specifications |
Item | Specification |
Appearance | White or light yellow powder |
Effective substance contene | ≥98% |
Melting point °C | 194°C-200.5°C |
Loss on drying | ≤0.3% |
Packaging & Storage |
Packaging: 20 kg/drum. Custom packaging can be discussed based on order quantity and transportation requirements.
Storage: For short-term storage, keep in a cool, well-ventilated area, with recommended temperatures below 15°C. For long-term storage, refrigeration at 2-8°C is recommended.
Shipping & Delivery |
Jinan, China
Immediately after payment
Qingdao / Tianjin / Shanghai / Ningbo
Sample Support
Samples are available for evaluation before bulk orders. Shipment arrangements depend on destination and applicable transportation requirements.
Factory & Quality Control |
Consistent quality control for each production batch.
Technical documents available upon request.
Samples available for product evaluation.
Custom specifications available upon request.
View Factory & Quality Control → View Technical Documents →
Applications |
Applications of 2,2'-Azobis[2-(imidazolin-2-yl)propane] dihydrochloride (VA044)
2,2'-Azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (CAS 27776-21-2) is a water-soluble azo compound widely used as a polymerization initiator and in oxidative stress research. Its molecular structure enables it to generate free radicals under controlled conditions, making it particularly suitable for polymerization processes and biochemical studies.
Polymerization Initiator
VA044 is commonly used as a water-soluble polymerization initiator. Its ability to initiate radical polymerization under mild conditions makes it suitable for synthesizing high molecular weight polymers.
Typical application areas include:
Synthesis of ultra-high relative molecular mass polyacrylamide
Hydrogel monomer solution polymerization
Free radical polymerization in aqueous systems
Production of functional polymers with specific properties
Oxidative Stress Research
In biochemical and biomedical research, VA044 serves as a model azo compound for generating free radicals in controlled experiments. This compound is used to study oxidative stress mechanisms in biological systems. AIPH (this compound)-induced cell death is directly proportional to free radical formation, enabling quantitative analysis of oxidative damage.
Key applications include:
Kinetic and mechanistic studies of oxidative stress in membranes, lipoproteins, cells, and animal models
Lipid peroxidation research
Investigation of antioxidant efficacy
Studies on reactive oxygen species (ROS) in biological systems
The final performance of VA044 in any application depends on the reaction conditions, concentration, temperature, and intended use. Customers should evaluate product suitability according to their specific requirements.
FAQ |
A: VA044 is mainly used in aqueous polymer synthesis, emulsion polymerization, polyacrylamide production, flocculant intermediates, and water‑based adhesive applications.
A: We can provide a variety of transportation methods, including express delivery for shipments under 25 kg, sea freight for large-volume cargo, and air freight upon request.
A:We respond within 24 hours and provide technical, order, and logistics support throughout the cooperation process.