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1185-53-1
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Packaging & Storage |
Packaging: 25 kg/drum. Custom packaging can be discussed based on order quantity and transportation requirements.
Storage: Tris HCL is hygroscopic. Store in tightly‑sealed containers in a cool, dry, well‑ventilated area at 15‑25 °C away from heat, light, oxidants and acids, and reseal promptly after opening to avoid moisture caking.
Storage & Handling Notes
For solid Tris HCL, prolonged exposure to high humidity or moisture may cause the material to absorb water and cake. Store in tightly sealed containers within a cool, dry and well‑ventilated environment, and avoid contact with acids and oxidizing agents.
Shipping & Delivery |
Jinan, China
Immediately after payment
Qingdao / Tianjin / Shanghai / Ningbo
Sample Support
Samples are available for evaluation before bulk orders. Shipment arrangements depend on destination and applicable transportation requirements.
Factory & Quality Control |
Consistent quality control for each production batch.
Technical documents available upon request.
Samples available for product evaluation.
Custom specifications available upon request.
View Factory & Quality Control → View Technical Documents →
Applications |
Applications of Tris(hydroxymethyl)aminomethane hydrochloride (Tris HCl)
Tris(hydroxymethyl)aminomethane hydrochloride (Tris HCl, CAS 1185-53-1) is a high-purity organic amine salt widely used as a biological buffer building block in biochemical reagent and biopharmaceutical formulations. Its molecular structure makes it particularly suitable for physiological-range buffer solutions, in-vitro diagnostic systems, and selected high-purity chemical synthesis processes.
Biological Buffers & Laboratory Reagents
Tris HCl is commonly used in the production of physiological pH buffer solutions for biological laboratory testing. Its amine-hydrochloride structure can support stable buffering capacity, low metal-ion interference, and formulation compatibility, making it suitable for life-science laboratory applications.
Typical application areas include:
Biological experiment buffer systems
Protein and nucleic acid purification reagents
Biochemical analysis kits
Cell culture medium additives
Molecular biology test reagents
Diagnostic Kits & Biopharmaceutical Raw Materials
Tris HCl can be used in formulation systems designed for in-vitro diagnostic kits, biopharmaceutical intermediates, and biological reagent products. Tris HCl-based buffer formulations may provide a useful balance of biocompatibility and solution performance, including resistance to pH drift, good water solubility, and low cytotoxicity.It is particularly suitable for formulations where stable pH buffering, high water-solubility, and low biotoxicity are required.
Tris HCl is also used as a pH-adjusting component in cosmetic formulations and organic chemical synthesis. These systems are applied in personal-care products and fine-chemical production requiring mild pH adjustment and stable formulation performance.
Typical applications include:
Cosmetic pH regulators
Water-based personal-care formulations
Organic synthesis intermediates
Fine-chemical raw materials
Tris HCl-based buffer systems can be used in in-vitro diagnostic (IVD) and biopharmaceutical applications, particularly where pH stability and biological safety are important performance considerations.
The final performance of Tris HCl in any buffer or formulation system depends on the complete formulation, raw-material purity, processing conditions, storage environment, and intended end use. Customers should evaluate product suitability according to their specific formulation and application requirements.
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